Systems Integration
Mathematics
Computer Science
Single-cell Biology

From laboratory experiments analyzing song bird sound evolution that shed light on the nature of intelligence to how cancer cell mobility mechanics work, the QSBC is involved with a variety of multi-disciplinary projects and activities. 

Aug 2021
Awards
Ivy Foundation Emerging Leader Grant Award 2021
Ivy Foundation Emerging Leader Grant Award website screenshot

Awarded to:

Rebecca Ihrie

Rebecca Ihrie, Ph.D.
Associate Professor, Cell & Developmental Biology
Vanderbilt University

Jul 2021
Publishing
Wound Detection Research
Research snapshot thumbnail

J.T. O'Connor, A.C. Stevens, E.K. Shannon, F.B. Akbar, K.S. LaFever, N.P. Narayanan, C.D. Gailey, M.S. Hutson, A. Page-McCaw “Proteolytic activation of Growth-blocking peptides triggers calcium responses through the GPCR Mthl10 during epithelial wound detection” Developmental Cell 2021 Jul 14: S1534-5807(21)00527-X. https://doi.org/10.1016/j.devcel.2021.06.020

Summary

Feb 2021
Speaking Engagements
ReMission Summit on brain tumor biology
Rebecca Ihrie speaking engagement

We’re here to rewrite the story of brain cancer. Let’s empower patients to take their lives back.

Oct 2020
International Collaboration
Fusion of Mathematics and Biology
Japanese meeting

The Japanese Core-to-core meeting titled "Fusion of Mathematics and Biology" was held online (via Zoom webinar) during October 26-28, 2020. Some participants gathered at an actual venue set up in Osaka University, Japan.

Read Full Write-Up by Naotoshi Nakamura.

Oct 2020
Research Publishing
Advancing Cancer Treatment
Press Release VU

A Vanderbilt cancer systems biology team has identified the enzymes that keep tumor cells growing in the presence of drug treatment, opening the door to stopping these cells dead in their tracks.

Full Article:
https://news.vanderbilt.edu/2020/10/21/interdisciplinary-melanoma-research-brings-understanding-of-cellular-resistance-to-cancer-treatment-opening-doors-to-new-cures/

Oct 2020
$500,000 NSF Grant
Future Manufacturing Seed Grant
Website Activities Image
Congratulations to Jamey Young, Ethan Lippman, Alissa Weaver, and John Wilson, who recently received a Future Manufacturing Seed Grant from NSF for their project “Enabling Technologies for Biomanufacturing EV-Based Therapeutics.”
 
Full Article:
Oct 2020
Graduate Courses
CPBP 8328 course​
CPBP Course Flyer
Vito Quaranta and Darren Tyson have implemented a Systems Thinking in Biomedicine course/seminar series, inspired by students Kavya Sharman and Cody Heiser, featuring internal and external speakers to present their research, followed by student discussions, which often include speakers.
 
Sep 2020
Quantitative Systems Biology Labs
Rebecca Ihrie Laboratory
Rebecca Ihrie
Aug 2020
Presentations
Junior Investigator Meeting for the NCI Cancer Systems Biology Consortium
Samantha Beik Meeting

The 2020 Junior Investigator (JI) Meeting for the NCI Cancer Systems Biology Consortium (CSBC), Physical Sciences – Oncology Network (PS-ON), and the Big Data Scientist Training Enhancement Program (BD-STEP) was held as a virtual meeting on August 27-28, 2020, bringing together systems biologists, physical scientists, and data scientists who work towards a better understanding of cancer and the resolution of fundamental questions in cancer research. This meeting aims to generate synergy between individuals with diverse skills and shared research interests.

Jul 2020
International Student Programs
Visiting student from France​
Jeremie

Jérémie Marlhens joined Quaranta Lab from Ecole Normale Superieure De Lyon (France) as a visiting research intern for 6 months. Jérémie worked with Darren Tyson and Quaranta Lab and Lopez Lab students to learn rule-based mechanistic modeling using PySB.

Mar 2020
International Group Programs
Collaboration with Japanese group​
Naotoshi

Naotoshi Nakamura, Specially Appointed Associate Professor in the Center for Mathematical Modeling and Data Science at Osaka University in Japan, joined us as a visiting faculty member at Vanderbilt. Dr. Nakamura worked to develop a mathematical model of the EphA2 receptor pathway, in order to explore its switch-like bistable behavior [promoting vs. inhibiting cell proliferation] in response to microenvironmental factors. 

Article | My 3 Weeks in Nashville

Mar 2020
Machine Learning
Image processing workshop
Hackathon

Darren Tyson, with the help of Mark III, organized a Cell Imaging Hackathon from March 4th-6th, held near Vanderbilt's campus, and welcoming attendees across the Midwest and West Coast to Nashville. Accepted challenges included: Multi-panel image registration Segmentation (competition) Rare cell type identification Quantification of PD1 asymmetry Morphology-based cell type calling.

Feb 2020
Collaboration with Fisk Program
Fisk-Vanderbilt Master's to PhD Program
Wajiha-Khalid

The Fisk-Vanderbilt Master’s to PhD Bridge Program works to improve the demographic representation in STEM. Wajiha Khalid took part in the program, joining the Quaranta Lab.

Jan 2020
Focused Working Groups
Single-cell Data Analysis Working Group
single cell image

This group meets every month to foster a computational biology community within Vanderbilt on single-cell genomics, by creating an interactive discussion and bootcamp style demonstration of software in the field on generated data. 

single cell image

Single-cell Data Analysis Working Group meeting

This group meets every month to foster a computational biology community within Vanderbilt on single-cell genomics, by creating an interactive discussion and bootcamp style demonstration of software in the field on generated data.

Samantha Beik Meeting

Junior Investigator Meeting for the NCI Cancer Systems Biology Consortium

The 2020 Junior Investigator (JI) Meeting for the NCI Cancer Systems Biology Consortium (CSBC), Physical Sciences – Oncology Network (PS-ON), and the Big Data Scientist Training Enhancement Program (BD-STEP) was held as a virtual meeting on August 27-28, 2020, bringing together systems biologists, physical scientists, and data scientists who work towards a better understanding of cancer and the resolution of fundamental questions in cancer research. This meeting aims to generate synergy between individuals with diverse skills and shared research interests.