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Precision and Plasticity in Animal Transcription

Over the past decade, our group has focused on discerning the molecular mechanisms that can reconcile how transcriptional control during animal development can be simultaneously precise (e.g. sharp in response […]

A Model of Non-modular Biochemical Oscillator and Switch

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Negative and positive feedback loops have been considered essential components for biological rhythms and switches, respectively. Research in systems biology focused on gene regulatory networks with intuitive appearances of feedback […]