Model-Driven Design of Optical Microscopy Experiments to Harvest Single-Cell Fluctuation Information while Rejecting Image Distortion Effects
Engineering & Science Building 048 Vanderbilt University, NashvilleModern fluorescence labeling and optical microscopy approaches make it possible to observe every stage of basic gene regulatory processes, even at the level of individual DNA, RNA, and protein molecules, […]
Combining Experiments with Computational Models to Engineer Tissue
Engineering & Science Building 048 Vanderbilt University, NashvilleThe most prevalent, devastating, and complex diseases of our time, such as diabetes, cardiovascular disease, cancer, and infectious diseases, involve the dynamic interactions of cells with one another and with […]
Logarithmic Signaling Regulates MAPK Stress Response and Survival
Bass Conference Room - PRB 436Signaling mechanisms enable cells to sense, respond, and adapt to changing environments. Understanding signal transduction mechanisms at both molecular and network levels is critical to characterize key proteins and reaction […]
Investigating Lung Diseases and the Use of Causal Modeling in Multi-Scale Medical Research
Light Hall 415ABCDThe advancement of technologies for high-throughput collection of molecular and clinical data, has inadvertently transformed biology and medicine. Integrating and co-analyzing these different data streams has become the research bottleneck […]
